Catalogue for Human Chromosome 18.
Login as a Guest user or Register
The mission of Gene-Centric Knowledgebase for human chromosome 18 is to represent, store and exchange of proteomics data for 275 protein-coding genes (UniProt, release 2015-11) in tabular form using the recommended by C-HPP format - heat map (Paik YK et al., 2012).
Knowledgebase consolidates public web-resources with proprietary experimental and predicted data, generated in course of Russian part of the "Human Proteome Project".
GenoCMS aggregates information from about 20 world public science web-resources and represents it in the section of chromosome 18:
- Availability 3D structure and antibodies
- Number of identifications in mass-spectoreter experiments
- Number of interacting partners
- Number of alternative splacing varians (ASs), post-translational modifications (PTMs) and single aminoacid polymorphisms (SAPs)
- Number of related publications and papers supporting gene association with cancer
- Evidence, trancription and expression Levels
- Position on chromosome and subcellular localization
- Protein molecular weight, gene and protein length
- Disease relationship
- Potential contaminants
The data of the mass-spectoreter experiments in five types of the biological samples are also provided:
- Protein copies number per 1 uL of human plasma, number of reads per kilobase
- Protein and transcript copies per liver cell
- Protein and transcript per HepG2 cell, number of reads per kilobase
- Synthetic proteotypic peptides
- Protein copies per HeLa cell
The data predicted from published and proprietary experimental results by using "in silico" approaches is special section of the GenoCMS:
- ASs, PTMs and SAPs
- Novel exons and introns
- Proteotypic peptides
- Interacting partner obtained using method virtual co-precipitation
Demo scenario presentation Download (pptx)
Any questions, suggestions, and feedback, please email to support@kb18.org
